Chicago White Sox vs. Houston Astros Prediction and MLB Sportsbook Tips – May 4, 2025

This article analyzes important variables that might affect the result of the Chicago White Sox vs. Houston Astros game that is scheduled for Sunday, May 4, at Rate Field. It will predict the anticipated result of the game by analyzing team performance, current trends, and the contributions of important players.

Match Overview

DateTime (ET)VenueTeamsLeague
Sunday, May 4, 20254:10 AMRate Field, Chicago, ILHouston Astros @ Chicago White SoxMLB

The Houston Astros will play the Chicago White Sox at Rate Field in Chicago on Sunday, May 4, 2025. 4:10 AM ET is the scheduled time for the first pitch. The White Sox are the underdogs at 3.05. The Astros are the favourites with a moneyline of 1.40. The game’s over/under is set at 8 runs, and Houston is the run line favourite (-1.5, 1.73).

Check out our other prediction for the St. Louis Cardinals vs. New York Mets game!

Chicago White Sox vs. Houston Astros Game Odds & Lines

Bet TypeOdds
MoneylineAstros: 1.40 • White Sox: 3.05
Run LineAstros -1.5: 1.73 • White Sox +1.5: 2.21
Total Runs (O/U)Over 8: 1.89 • Under 8: 1.89

Starting Pitchers

TeamPitcherRecord (W-L)ERA
Houston AstrosHunter Brown4-11.22
Chicago White SoxDavis Martin1-33.24

Weather & Ballpark Conditions

  • Forecast: Partly cloudy, 48°F
  • Wind: Blowing left to right at 16 mph
  • Humidity: 76%
  • Ballpark Factor: Cool temperatures and crosswinds give pitchers a slight advantage.

Key Insights & Betting Trends

  • The Astros are 67% likely to win.
  • There is a 54% likelihood that the Astros will cover the run line.
  • The probability that Over/Under will exceed Astros’ is 51%.
  • Brown, the hunter, has an ERA of 1.22.
  • The White Sox’s Davis Martin has a 3.24 ERA.

Expert Picks & Recommended Bets

  • Moneyline: Astros @ 1.40
  • Run Line: Astros -1.5 @ 1.73
  • Total Runs: Over 8 @ 1.89

Chicago White Sox vs. Houston Astros Predicted Outcome

Thanks to Hunter Brown’s outstanding pitching and a favourable matchup with Davis Martin, the Astros are well-positioned to defeat the White Sox. The Astros’ offence should generate enough runs to cover the spread, but the game’s circumstances indicate a slight advantage for pitchers.

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