Cubs vs. Reds: August 6, 2025 – Betting Preview, Odds & Predictions

The Chicago Cubs will host the Cincinnati Reds at Wrigley Field on August 6, 2025. Chicago is the favoured in a high-scoring affair based on key trends and pitcher matchups. We examine the best bets, odds, and expert predictions for this NL game.

Match Overview

Date: Wednesday, August 6, 2025
Time: 2:20 p.m. ET
Venue: Wrigley Field, Chicago, IL
Teams: Cincinnati Reds vs. Chicago Cubs
League: Major League Baseball (MLB)

On Wednesday, August 6, 2025, the Cincinnati Reds will face the Chicago Cubs at Wrigley Field in Chicago. First pitch is scheduled for 2:20 p.m. ET. The Cubs are favored with a moneyline of –186, while the Reds are underdogs at +154. Chicago is also the run line favorite (–1.5 at +119), and the game’s over/under is set at 7.5 runs (Over +103 / Under –124)

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Game Odds & Lines

Bet Type	Odds
Moneyline	Reds: +154 • Cubs: –186
Run Line	Reds +1.5: –142 • Cubs –1.5: +119
Total Runs	Over 7.5: +103 • Under 7.5: –124

Starting Pitchers

Team	Pitcher Name	W‑L	ERA
Reds (Away)	Andrew Abbott (LHP)	8‑1	2.15
Cubs (Home)	Cade Horton (RHP)	5‑3	3.42

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Last 5 Games Record

Team	Last 5 Games Record
Cincinnati	W, W, L, L, W
Chicago	L, L, W, W, – (final only)

Head‑to‑Head Record (2025 Season)

Matchup	Result
Cubs vs. Reds	Cubs have won previous two games of series

Weather & Ballpark Conditions

Forecast: Fog in the morning, clearing to mostly sunny with highs around mid‑80s°F by early afternoon.
Wind: Light, variable — minimal impact on flight.
Humidity: Moderate to high during start, dropping into afternoon.
Ballpark Factor: Neutral overall; early fog could suppress offense early, but warm afternoon temps may favor hitters as skies clear.

Key Insights & Betting Trends

• Cubs win 79% when favored at least –186 this season
• Reds successful in underdog role only 53% of time
• Cubs ATS recent struggles: 3–7 over last 10
• Total lines hit the over ~40% in recent Cubs home games
• Abbott boasts elite 2.15 ERA versus Cubs struggling bats

Expert Picks & Recommended Bets
Moneyline: Cubs @ –186
Run Line: Cubs –1.5 @ +119
Total Runs: Over 7.5 @ +103

Predicted Outcome

Chicago should salvage the finale at home behind Abbott’s dominant season performance and Horton’s solid, if less impressive, ERA. The Cubs’ better home offense and Abbott’s left‑handed edge create a betting edge. Expect a tight game where Chicago ekes out a win—7–4 or 6–3—and the total to clear the over trigger with scoring in later innings.

Sources: https://www.oddsshark.com/nba/, https://www.cbssports.com/nba, https://www.foxsports.com/articles/nba/, https://www.mybookie.ag/sportsbook/