Yankees vs Mariners 2025: Prediction, odds, betting tips, favourites, line up

Yankees vs Mariners: The Yankees host the Mariners Thursday at 7:05 p.m. ET, with Marcus Stroman facing Bryan Woo. Seattle is a slight favorite, but predictive models give the Yankees a strong 63% chance to cover the +1.5 run line. The best bet is Yankees +1.5 (-160). Bettors can unlock bonus offers with BetMGM, Bet365, or DraftKings promo codes.

The New York Yankees return to action Thursday night as they host the Seattle Mariners in an interleague showdown at Yankee Stadium. First pitch is scheduled for 7:05 p.m. ET. Marcus Stroman (1-1, 7.45 ERA) gets the start for the Yankees, while Bryan Woo (8-4, 2.77 ERA) will take the mound for the Mariners. The top betting value for this matchup points to the Yankees +1.5 on the run line at -160.

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New York Yankees vs Seattle Mariners: Seattle Slight Favorite, but Yankees Backed to Cover

Oddsmakers have the Mariners as narrow road favorites at -120 on the moneyline, with the Yankees priced at +104. However, most of the betting attention is on the run line, where the Yankees are +1.5 at -160 odds. That means a one-run loss by New York would still cash this bet.

Dimers.com’s predictive analytics model gives the Mariners a 51% chance of winning outright. But the same model also gives the Yankees a 63% probability of covering the +1.5 spread, suggesting they’re more likely to keep this one close—even if they don’t walk away with the win.

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Yankees vs Mariners: Starting Pitchers

Seattle’s Bryan Woo has been impressive all season, sporting an 8-4 record with a 2.77 ERA. His command and control have kept opposing bats quiet, and he’s given the Mariners a chance to win nearly every time out.

On the flip side, Marcus Stroman is still looking to lock in with the Yankees. After a strong past season in Chicago, Stroman has dealt with inconsistency in New York. His 7.45 ERA is inflated, but he’s capable of quality starts—especially at home, where he’ll need to keep Seattle’s lineup in check early.

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Yankees vs Mariners Odds & bets

Run Line, Moneyline, and Total Odds Breakdown

Here are the current odds for Thursday’s matchup, based on the latest updates from top sportsbooks:

Run line: Mariners -1.5 (+136), Yankees +1.5 (-160)

Moneyline: Mariners -120, Yankees +104

Total Runs: Over/Under 9 (-110/-105)

While Seattle holds a slight edge straight up, the betting value leans toward New York when taking the +1.5 run line. That’s backed up by data simulations and betting market trends leading into the game.

Yankees vs Mariners: Public Betting

Bettors have been split across the key markets. The moneyline has seen relatively even action due to the close odds, while the run line has attracted sharp interest on the Yankees side. With their solid record at home and the tendency to stay in games late, New York offers value when getting a run and a half.

As for the total, the over/under of 9 runs has been steady with books expecting a mid-scoring game. Advanced simulations put the total outcome at an even 50-50 split, making it a tougher call for bettors looking at the run total market.

Yankees vs Mariners: Best Bet: Yankees +1.5 (-160)

Considering the matchup, pitching data, and simulation probabilities, the best bet is the Yankees +1.5 at -160. This option allows for a tight loss or potential upset win while still cashing the ticket. For bettors seeking consistency and edge, this is the smartest way to play Thursday night’s matchup.

Odds are subject to change, so always check your sportsbook before locking in bets.