St. Louis Cardinals vs. Washington Nationals Pirates MLB Match Prediction and Tips – May 11, 2025

Table of Contents

Sunday, May 11, is the noon game between the St. Louis Cardinals (18–19) and the Washington Nationals (16–21) at the nation’s capital. The Cardinals will send veteran right-hander Miles Mikolas to the mound, while the Nationals will reply with left-hander MacKenzie Gore. Both clubs are trying to pick up steam as they try to climb the divisional standings. Get expert insight on pitching matchups, core hitters, and strategy angles for this game.

Match Overview

DateTime (ET)VenueTeamsLeague
Sunday, May 11, 20251:35 PMNationals Park, Washington, D.C.St. Louis Cardinals @ Washington NationalsMLB

Intro Content

On Sunday, May 11, 2025, the St. Louis Cardinals will take on the Washington Nationals at Nationals Park in Washington, D.C. The first pitch will be made at 1:35 PM ET. The Cardinals are the favourites with a moneyline of 1.85, while the Nationals are the underdogs at 2.00. St. Louis is the run line favourite (-1.5, 2.41) and the over/under for the game is set at 9.5 runs.

Check out our other prediction for the Atlanta Braves vs. Pittsburgh Pirates game!


Game Odds & Lines

Bet TypeOdds
MoneylineCardinals: 1.85 • Nationals: 2.00
Run LineCardinals -1.5: 2.41 • Nationals +1.5: 1.57
Total Runs (O/U)Over 9.5: 1.91 • Under 9.5: 1.91

Note: Odds are presented in decimal format.


Starting Pitchers

TeamPitcherRecord (W-L)ERA
CardinalsAndre Pallante2-24.75
NationalsTrevor Williams2-35.86

Weather & Ballpark Conditions

  • Forecast: Partly cloudy, 72°F
  • Wind: Blowing in from left field at 10 mph
  • Humidity: 31%
  • Ballpark Factor: Slight edge to pitchers based on today’s conditions

Last 5 Games Record

TeamRecord (W-L)Recent Performance
Cardinals4-1W vs. Nationals (10-0), W vs. Pirates (5-0), W vs. Pirates (6-3), W vs. Mets (6-5), L vs. Mets (4-5)
Nationals2-3L vs. Cardinals (0-10), L vs. Guardians (6-8), L vs. Guardians (1-4), W vs. Guardians (10-9), W vs. Reds (4-1)

Head-to-Head Record

  • All-Time Record: Cardinals lead 340-313
  • Last 20 Games: Cardinals lead 12-8

Key Insights & Betting Trends

  • The Cardinals have won seven of their past 10 games.
  • The Nationals have been shut out in three of their last five games.
  • The Cardinals have won five shutout games this season.
  • Trevor Williams of the Nationals has allowed 15 earned runs in his previous three outings.
  • The Cardinals’ offensive has averaged over five runs per game over the past five games.

Check out our other prediction for the Atlanta Braves vs. Pittsburgh Pirates game!


Expert Picks & Recommended Bets

  • Moneyline: Cardinals @ 1.85
  • Run Line: Cardinals -1.5 @ 2.41
  • Total Runs: Over 9.5 @ 1.91

St. Louis Cardinals vs. Washington Nationals Predicted Outcome

The Cardinals are in a strong position to win another game because of their recent offensive surge and the Nationals’ struggles on the mound, especially with Trevor Williams’ recent performances. St. Louis should score early and keep up their momentum the entire time.

Check out our other prediction for the Atlanta Braves vs. Pittsburgh Pirates game!

Sources: https://baseball.realgm.com/, https://www.betus.com.pa/sportsbook/mlb/, https://sportsbook.fanduel.com/navigation/mlb, https://www.statsinsider.com.au/

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