New York Yankees vs. San Diego Padres Prediction, Odds & Betting Tips – May 7, 2025

Table of Contents

On Wednesday, May 7, the Yankees (20–15) play the Padres (17–17) in a cross-league match at Yankee Stadium. In response, New York sends ace Gerrit Cole to the mound, while San Diego sends left-hander Blake Snell. Both teams are seeking to accelerate in highly competitive divisional races. This midweek matchup presents a solid DFS chance because of the favourable weather for hitters, excellent pitching choices, and potential momentum. Get expert insight on pitching matchups, core hitters, and strategy angles for this game.

Intro & Slate Overview

Today’s Yankees vs Padres MLB DFS slate features a matchup between the New York Yankees and the San Diego Padres. The game will take place at Yankee Stadium, with a projected total of 9 runs. The spread favors the Yankees, with NYY -1.5, setting up for a thrilling contest.

Check out our other prediction for the Arizona Diamondbacks vs. New York Mets game!

Top Pitching Picks

Starting pitcher Gerrit Cole comes into this game priced at $10,200, with a strong track record against right-handed hitters and an excellent strikeout rate. He is a top-tier option for today’s slate. On the other side, Blake Snell offers a salary discount at $8,600 and could be a solid GPP option for those looking for upside at a lower cost.

Top Hitter & Matchups

Aaron Judge is expected to be one of the top performers in this game. With a price tag of $5,800 and a favorable matchup against left-handed pitching, he’s a strong cash and GPP play. His power potential in Yankee Stadium, a hitter-friendly park, makes him a must-play for those looking for home run upside.

Stack Strategy

With the total set at 9, stacking the Yankees seems like a smart choice today. Players like Aaron Judge, Giancarlo Stanton, and Josh Donaldson could provide plenty of pop, especially with the favorable conditions. Look to leverage these hitters for upside, particularly if the Yankees can get to Snell early.

Value Plays

For value plays, consider hitters priced under $3,500 who may have favorable matchups based on recent form and splits. These budget plays could help free up salary for premium hitters. Always monitor starting lineups to spot last-minute changes.

Weather Impact

Weather conditions in New York look clear, but winds are expected to blow out to left-center field at 12mph, potentially aiding power hitters and increasing the ball’s carry. This could benefit right-handed hitters like Aaron Judge.

Betting Angle & Game Script

The Yankees are favored at -1.5, with a total set at 9 runs. This indicates a moderate expectation for scoring, with the Yankees likely to generate offense. DFS players should lean into this game by prioritizing both lineups or focusing on pitching if you expect a dominant performance from Cole.

Check out our other prediction for the Toronto Blue Jays vs. Los Angeles Angels game!

Pitching Strategy Deep Dive

Gerrit Cole stands out as the top option on this slate, especially with his ability to rack up strikeouts against high-K teams. While his $10,200 price tag is high, the potential upside and floor he offers in a high-leverage matchup make him a must-have for cash games. Blake Snell is more of a GPP play, offering salary relief with the potential for a strong performance.

Game Environment Analysis

The game at Yankee Stadium offers an ideal environment for hitters. With winds blowing out to left-center field and the total set at 9, this could be a high-scoring game. The Yankees’ lineup is stacked with right-handed power, and with Snell’s command issues, they could take advantage of the situation.

Advanced Metrics Matchup

Look into advanced stats like wOBA and ISO for both teams, as this game presents a clash between high-powered offense (Yankees) and a pitcher (Snell) who may struggle with control. Cole’s ability to strike out hitters at a high rate gives him a strong edge over Padres hitters.

Slate Construction & Ownership Leverage

With a 9-game slate, many DFS players will flock to high-profile games like Yankees vs. Padres. However, focusing on lesser-owned teams or players from the Padres, like Manny Machado or Juan Soto, could help gain leverage in larger-field tournaments.

Check out our other prediction for the Chicago White Sox vs. Kansas City Royals game!

Final Thoughts & Strategy Wrap-up

This slate offers a combination of elite pitching in Gerrit Cole and power hitters in Aaron Judge and Giancarlo Stanton. With favorable weather conditions and a high total, stacking the Yankees seems like a great strategy, but keep an eye on Padres’ hitters for potential leverage in GPPs. Monitor lineup news and weather changes as the game approaches.

Sources: https://baseball.realgm.com/, https://www.betus.com.pa/sportsbook/mlb/, https://sportsbook.fanduel.com/navigation/mlb, https://www.statsinsider.com.au/

Share it :