St. Louis Cardinals vs. Washington Nationals Match Prediction and MLB Tips – May 10, 2025

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On Saturday, May 10, the Cardinals (17–19) will start a weekend series against the Nationals (18–18) at Washington. After right-hander Erick Fedde is sent to the mound by St. Louis, Washington replies with Mitchell Parker. Both teams are now trading at around.500 and are attempting to generate momentum in the first part of May. Get expert insight on pitching matchups, core hitters, and strategy angles for this game.

Match Overview

DateTime (ET)VenueTeamsLeague
Saturday, May 10, 20256:45 PMNationals Park, Washington, D.C.St. Louis Cardinals @ Washington NationalsMLB

On Saturday, May 10, 2025, the St. Louis Cardinals will take on the Washington Nationals at Nationals Park in Washington, D.C. The first pitch is scheduled at 6:45 PM ET. The Nationals are the favourites with a moneyline of 1.87, while the Cardinals are the underdogs at 1.95. Washington is the run line favourite (-1.5, 2.75), while the over/under for the game is set at 8.5 runs.

Check out our other prediction for the Texas Rangers vs. Detroit Tigers game!


Game Odds & Lines

Bet TypeOdds
MoneylineNationals: 1.87 • Cardinals: 1.95
Run LineNationals -1.5: 2.75 • Cardinals +1.5: 1.48
Total Runs (O/U)Over 8.5: 1.91 • Under 8.5: 1.91

Starting Pitchers

TeamPitcherW-LERA
St. Louis CardinalsErick Fedde2-34.78
Washington NationalsMitchell Parker3-23.48

Weather & Ballpark Conditions

  • Forecast: Clear skies, 72°F
  • Wind: Blowing out to left at 9 mph
  • Humidity: 55%
  • Ballpark Factor: Slight edge to hitters due to wind conditions

Last 5 Games Record

TeamDateOpponentResult
Washington NationalsMay 7vs. CLEL 6-8
May 6vs. CLEL 1-9
May 6vs. CLEW 10-9
May 4@ CINW 4-1
May 3@ CINW 11-6
St. Louis CardinalsMay 7vs. NYMW 5-4
May 6vs. CINL 1-3
May 5vs. ATLW 10-4
May 4vs. ATLL 2-5
May 3vs. ATLW 6-3

Head-to-Head Record

DateVenueResult
July 31, 2022WashingtonCardinals 5, Nationals 0

Key Insights & Betting Trends

  • Nationals have a 53% chance of winning.
  • The Cardinals have a 64% chance of covering the +1.5 line.
  • A 53% chance of under 8.5 runs
  • Mitchell Parker of the Nationals has a 3.48 ERA.
  • Erick Fedde of the Cardinals has an ERA of 4.78.

Check out our other prediction for the Atlanta Braves vs. Pittsburgh Pirates game!


Expert Picks & Recommended Bets

  • Moneyline: Nationals @ 1.87
  • Run Line: Nationals -1.5 @ 2.75
  • Total Runs: Under 8.5 @ 1.91

St. Louis Cardinals vs. Washington Nationals Predicted Outcome

Mitchell Parker’s strong play this season and the Nationals’ home field advantage put them in a strong position to defeat the Cardinals by a slim margin. But given that both teams have recently displayed erratic play, anticipate a hotly contested match that could end in a low-scoring contest.

Check out our other prediction for the Toronto Blue Jays vs. Seattle Mariners game!

Sources: https://baseball.realgm.com/, https://www.betus.com.pa/sportsbook/mlb/, https://sportsbook.fanduel.com/navigation/mlb, https://www.statsinsider.com.au/

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