Cubs vs Orioles Prediction: Chicago Favored in Friday’s Matchup at Wrigley

Chicago is the moneyline favourite when the Cubs play the Orioles at Wrigley on Friday afternoon. The Cubs aim to defeat a tough Baltimore team led by Trevor Rogers in a game that is likely to be high-scoring thanks to Cade Horton and exceptional power hitting.

Match Overview

DateTime (ET)VenueCity, State
Friday, August 1, 20252:20 p.m. ETWrigley FieldChicago, Illinois

Teams: Baltimore Orioles vs. Chicago Cubs
League: Major League Baseball (MLB)


Intro
On Friday, August 1, 2025, the Baltimore Orioles will face the Chicago Cubs at Wrigley Field in Chicago, Illinois. First pitch is scheduled for 2:20 p.m. ET. The Cubs are favored with a moneyline of –148, while the Orioles are underdogs at +123. Chicago is also the run line favorite (–1.5, +149 odds), and the game’s over/under is set at 7.5 runs (Over –105, Under –115).

ALSO READ: Braves vs. Reds: Cincinnati Favored in Series Finale at Home


Game Odds & Lines

Bet TypeOdds
MoneylineOrioles: +123 • Cubs: –148
Run LineOrioles +1.5: –182 • Cubs –1.5: +149
Total Runs (O/U)Over 7.5: –105 • Under 7.5: –115

Starting Pitchers

TeamStarter
Baltimore OriolesTrevor Rogers (4‑1, 1.49 ERA)
Chicago CubsCade Horton (4‑3, 3.67 ERA)

Weather & Ballpark Conditions

Forecast: Data not provided in sources. Ballpark: typical Wrigley Field day game, likely mild. Wind, humidity, ballpark factor: not specified in available previews.


Last 5 Games Record

TeamLast 5 Games RecordRuns Per Game (Last 5)
Chicago CubsWon 3, Lost 2 (3–2)~4.8 rpg
Baltimore OriolesWon 3, Lost 2 (3–2)~7.5 rpg

Head‑to‑Head Record

Season series prior to this game not specified exactly, but recent matchups show Cubs holding the edge. No detailed head-to‑head table available in sources.


  • Cubs have won ~67–74% as moneyline favorites
  • Cubs offense ranks top‑3 in HRs and AVG
  • Orioles batting .245 with middling production
  • Cubs over total hit rate high (over in ~55% games)
  • Orioles ~45% win rate as moneyline underdogs

  • Moneyline: Cubs @ –148
  • Run Line: Cubs –1.5 @ +149
  • Total Runs: Over 7.5 @ –105
    (computer models and experts favor Cubs win and Over 7.5)

Predicted Outcome

Chicago should secure the win here, riding a potent offense and consistent run production while Trevor Rogers’ strong ERA (1.49) might keep Baltimore in it early. But Chicago’s home-field edge, recent scoring rhythm, and favorable power profiles give them the edge. Look for the Cubs to come out on top, likely covering the run line and pushing the total over 7.5 runs.

Courtesy: https://www.covers.com/, https://www.globenewswire.com, https://www.oddsshark.com, https://www.mytopsportsbooks.com/, https://www.foxsports.com/

Veer

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