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Tampa Bay Rays vs. Chicago White Sox Prediction & Odds-MLB 2025

Home | MLB | Tampa Bay Rays vs. Chicago White Sox Prediction & Odds-MLB 2025

On Thursday, September 11, the Tampa Bay Rays (72-73) travel to Chicago to face the White Sox (56-90) at Guaranteed Rate Field. First pitch is set for 2:10 PM ET. The Rays are slight favourites in this one, and both the pitching matchup and recent trends suggest this could be a tight, entertaining game.


Match Overview

DetailInformation
DateThursday, 11 September 2025
Time2:10 PM ET
VenueGuaranteed Rate Field, Chicago, IL
TeamsTampa Bay Rays vs. Chicago White Sox
LeagueMajor League Baseball (MLB)

The Tampa Bay Rays will visit the Chicago White Sox on Thursday, September 11, 2025. The game begins at 2:10 PM ET. The Rays are listed as slight favourites with a moneyline around -142 (varies by source), while the White Sox are underdogs at roughly +120. The over/under is set around 8 runs, and the run line favours the Rays (-1.5).

ALSO READ: Orioles vs. Pirates Prediction & Betting Preview-MLB 2025


Game Odds & Lines

Bet TypeOdds
MoneylineTampa Bay ― -142 • Chicago +120
Run LineRays -1.5: about +115 • White Sox +1.5: about -135
Total Runs (O/U)Over 8: roughly -115 • Under 8: about -105

Starting Pitchers

TeamStarting Pitcher
Tampa Bay RaysIan Seymour (record ~3-1, ERA ~2.89)
Chicago White SoxShane Smith (5-7, ERA ~3.95)

Weather & Ballpark Conditions

  • Forecast: (Data not explicitly available) but being a day game in Chicago in mid-September, conditions are likely to be mild.
  • Ballpark Factor: Guaranteed Rate Field tends to be somewhat neutral to slightly favourable for hitters, especially if winds are in. (No detailed wind/humidity data found.)

Last 5 Games Record

TeamLast 5 Games
Tampa Bay RaysMixed: recent performance has been inconsistent.
Chicago White SoxAlso uneven, but showing some flashes—especially at home.

Head-to-Head Record

  • Recent matchups have leaned toward more scoring, and the games between these two clubs have often gone over the total.
  • The Rays have traditionally had an edge over the White Sox in recent series.

  • Ian Seymour has been strong this season, posting good ERA numbers and decent strikeout metrics, though some home/away splits show variation.
  • Shane Smith has allowed a fair number of home runs, especially to left-handed hitters.
  • Games involving the White Sox have trended toward the over; similarly, Rays vs White Sox matchups often surpass the total run line.
  • The Rays are in a must-win mindset to stay relevant in the Wild Card chase.

  • Moneyline: Rays @ -142
  • Run Line: Rays -1.5
  • Total Runs: Over 8 runs

Predicted Outcome

Ian Seymour’s recent form gives the Rays a slight edge, particularly if they can get through the early innings cleanly. Shane Smith is capable, but his tendency to give up homers could hurt him in a game where the White Sox offense, though inconsistent, has shown bursts, especially at home. Expect a moderately high-scoring game where the Rays do just enough. Predicted final score: Rays 6-4 White Sox.

Sources: https://www.oddsshark.com/, https://www.cbssports.com/, https://www.foxsports.com/, https://www.mybookie.ag/sportsbook/

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